Adenosine receptors: new opportunities for future drugs

Bioorg Med Chem. 1998 Jun;6(6):619-41. doi: 10.1016/s0968-0896(98)00038-8.

Abstract

This review summarises current knowledge on adenosine receptors, an important G protein-coupled receptor. The four known adenosine receptor subtypes A1, A2A, A2B, and A3 are discussed with special reference to the opportunities for drug development.

Publication types

  • Review

MeSH terms

  • Adenosine / metabolism
  • Adenosine / physiology
  • Animals
  • GTP-Binding Proteins / metabolism*
  • Humans
  • Ligands
  • Models, Molecular
  • Pharmaceutical Preparations* / chemistry
  • Pharmaceutical Preparations* / metabolism
  • Receptors, Purinergic P1 / chemistry
  • Receptors, Purinergic P1 / drug effects*
  • Receptors, Purinergic P1 / physiology
  • Structure-Activity Relationship

Substances

  • Ligands
  • Pharmaceutical Preparations
  • Receptors, Purinergic P1
  • GTP-Binding Proteins
  • Adenosine