Minor salivary gland hyalinisation and amyloidosis in low-grade lymphoma of MALT

J Oral Pathol Med. 1998 May;27(5):229-32. doi: 10.1111/j.1600-0714.1998.tb01947.x.


Two patients with low-grade lymphoma of mucosa-associated lymphoid tissue (MALT) arising in primary Sjögren's syndrome developed solitary nodules in their lips. Histologically both lesions showed enlargement and hyalinisation of single minor salivary glands with acinar atrophy, loss of most ducts and conversion into almost acellular sclerotic eosinophilic masses. In one case the lesion was shown to contain an amyloid component. No amyloid was detected in the second case but deposition of collagen and basement membrane and sclerotic neoplasm were excluded.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amyloid / analysis
  • Amyloidosis / complications
  • Amyloidosis / pathology*
  • Atrophy
  • Basement Membrane / pathology
  • Collagen / analysis
  • Eosinophilia / pathology
  • Female
  • Humans
  • Hyalin / chemistry*
  • Lip Diseases / complications
  • Lip Diseases / pathology*
  • Lymphoma, B-Cell, Marginal Zone / complications*
  • Middle Aged
  • Salivary Ducts / pathology
  • Salivary Gland Diseases / complications
  • Salivary Gland Diseases / pathology
  • Salivary Glands, Minor / pathology*
  • Sclerosis
  • Sjogren's Syndrome / complications


  • Amyloid
  • Collagen