Severe expression of corpus gastritis is characteristic in gastric cancer patients infected with Helicobacter pylori

Br J Cancer. 1998 Jul;78(2):263-6. doi: 10.1038/bjc.1998.475.


In 50 Helicobacter pylori-infected gastric carcinoma patients the corpus gastritis was significantly higher than in matched H. pylori-positive control subjects (P < 0.01). Atrophy and intestinal metaplasia (IM) occurred significantly more often in the antrum of carcinoma patients (P < 0.01). The odds ratio for gastric carcinoma was 8.85 for high-grade corpus gastritis and 8.04 when atrophy in the antrum was present.

MeSH terms

  • Female
  • Gastric Mucosa / pathology
  • Gastritis / etiology*
  • Helicobacter Infections / complications*
  • Helicobacter pylori*
  • Humans
  • Male
  • Middle Aged
  • Stomach Neoplasms / etiology*
  • Stomach Neoplasms / pathology