Left-sided atrioventricular nodal ablation using the transseptal approach: clinico-histopathologic correlation

J Cardiovasc Electrophysiol. 1998 Jul;9(7):757-60. doi: 10.1111/j.1540-8167.1998.tb00962.x.


To our knowledge, prograde access to the left ventricle to perform a left-sided AV node (AVN) ablation has not been reported. We present the case of a patient with Noonan's syndrome and supravalve aortic stenosis who required aortic valve replacement with a mechanical valve. Due to chronic atrial fibrillation, a transvenous pacing system was implanted and transcatheter radiofrequency ablation of the AVN was performed. Attempts at right-sided AVN ablation were unsuccessful. Due to the presence of the mechanical aortic valve, a left-sided AVN ablation was performed successfully using the transseptal approach. The patient died suddenly 6 months after the procedure, and the histologic study of the heart is reported.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Atrial Fibrillation / pathology
  • Atrial Fibrillation / physiopathology
  • Atrial Fibrillation / surgery
  • Atrioventricular Node / pathology
  • Atrioventricular Node / physiopathology
  • Atrioventricular Node / surgery*
  • Catheter Ablation* / methods
  • Fatal Outcome
  • Follow-Up Studies
  • Heart Rate
  • Heart Septum
  • Humans
  • Male
  • Tachycardia, Supraventricular / pathology
  • Tachycardia, Supraventricular / physiopathology
  • Tachycardia, Supraventricular / surgery*
  • Tachycardia, Ventricular / pathology
  • Tachycardia, Ventricular / physiopathology
  • Tachycardia, Ventricular / surgery*