Percutaneous biopsy in diffuse renal disease: comparison of 18- and 14-gauge automated biopsy devices

J Vasc Interv Radiol. Jul-Aug 1998;9(4):651-5. doi: 10.1016/s1051-0443(98)70338-0.


Purpose: To compare 18-gauge-needle automated biopsy guns to 14-gauge systems for diagnostic efficacy and safety in percutaneous renal biopsy.

Materials and methods: One hundred sixty-one computed tomographic (CT) guided biopsies for diffuse renal disease were retrospectively reviewed. An automated biopsy gun with an 18-gauge needle was used in 74 procedures, and a 14-gauge needle was used in 87 cases.

Results: Adequate tissue for histologic diagnosis was obtained in 96% (71 of 74) of cases with use of the 18-gauge needle, compared with 99% (86 of 87) in the 14-gauge group. The mean glomeruli per specimen were 10.7 and 13.7, respectively. Major hemorrhagic complications occurred in two cases (2.7%) of the 18-gauge group and in three cases (3.4%) of the 14-gauge group.

Conclusion: The use of a biopsy gun with an 18-gauge needle provides high tissue recovery rate, comparable to that with the 14-gauge system. The complication rate was acceptably low, with no statistically significant difference from the 14-gauge needles (P = .80).

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Needle / instrumentation*
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Equipment Design
  • Female
  • Humans
  • Kidney / diagnostic imaging
  • Kidney / pathology
  • Kidney Diseases / diagnostic imaging
  • Kidney Diseases / pathology*
  • Male
  • Middle Aged
  • Needles
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / instrumentation*