[Mycobacterium chelonae cutaneous infection: efficacy of prolonged treatment by clarithromycin]

Ann Dermatol Venereol. 1997;124(3):251-3.
[Article in French]

Abstract

Introduction: Mycobacterium chelonae is an ubiquitous mycobacterium which is exceptionally pathogenic. It can cause localized skin infections which are difficult to treat because of multiple drug-resistance.

Case report: A 87-year-old woman with bullous pemphigoid was treated with long-term prednisone and developed a skin infection due to M. Chelonae. Treatment with clarithromycin was successful, but relapse occurred 6 months after withdrawal of the antibiotic.

Discussion: Clarithromycin is effective in single drug regimen for M. Chelonae infection, but the duration of treatment should be long when immunosuppression cannot be avoided.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Clarithromycin / therapeutic use
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunocompromised Host
  • Leg Dermatoses / drug therapy
  • Leg Dermatoses / etiology*
  • Mycobacterium Infections, Nontuberculous / complications*
  • Mycobacterium Infections, Nontuberculous / drug therapy
  • Mycobacterium Infections, Nontuberculous / microbiology
  • Mycobacterium chelonae*
  • Pemphigoid, Bullous / complications
  • Pemphigoid, Bullous / drug therapy
  • Prednisone / therapeutic use
  • Skin Diseases, Infectious / drug therapy
  • Skin Diseases, Infectious / etiology*
  • Skin Diseases, Infectious / microbiology
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Glucocorticoids
  • Clarithromycin
  • Prednisone