The AP2/EREBP family of plant transcription factors

Biol Chem. 1998 Jun;379(6):633-46. doi: 10.1515/bchm.1998.379.6.633.


AP2 (APETALA2) and EREBPs (ethylene-responsive element binding proteins) are the prototypic members of a family of transcription factors unique to plants, whose distinguishing characteristic is that they contain the so-called AP2 DNA-binding domain. AP2/ REBP genes form a large multigene family, and they play a variety of roles throughout the plant life cycle: from being key regulators of several developmental processes, like floral organ identity determination or control of leaf epidermal cell identity, to forming part of the mechanisms used by plants to respond to various types of biotic and environmental stress. The molecular and biochemical characteristics of the AP2/EREBP transcription factors and their diverse functions are reviewed here, and this multigene family is analyzed within the context of the Arabidopsis thaliana genome sequence project.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Arabidopsis / genetics*
  • Arabidopsis Proteins
  • DNA-Binding Proteins / genetics
  • Genes, Plant*
  • Homeodomain Proteins / genetics
  • Molecular Sequence Data
  • Nuclear Proteins / genetics
  • Plant Growth Regulators / genetics*
  • Plant Proteins / genetics
  • Transcription Factors / genetics*


  • APETALA2 protein, Arabidopsis
  • Arabidopsis Proteins
  • DNA-Binding Proteins
  • Homeodomain Proteins
  • Nuclear Proteins
  • Plant Growth Regulators
  • Plant Proteins
  • Transcription Factors
  • ethylene-responsive element binding protein