Effect of the extract of Annona muricata and Petunia nyctaginiflora on Herpes simplex virus

J Ethnopharmacol. 1998 May;61(1):81-3. doi: 10.1016/s0378-8741(98)00013-0.


Annona muricata (Annonaceae) and Petunia nyctaginiflora (Solanaceae) were screened for their activity against Herpes simplex virus-1 (HSV-1) and clinical isolate (obtained from the human keratitis lesion). We have looked at the ability of extract(s) to inhibit the cytopathic effect of HSV-1 on vero cells as indicative of anti-HSV-1 potential. The minimum inhibitory concentration of ethanolic extract of A. muricata and aqueous extract of P. nyctaginiflora was found to be 1 mg/ml.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chlorocebus aethiops
  • Herpesvirus 1, Human / drug effects*
  • Herpesvirus 1, Human / isolation & purification
  • Herpesvirus 1, Human / pathogenicity
  • Humans
  • India
  • Microbial Sensitivity Tests
  • Plant Extracts / pharmacology
  • Plants, Medicinal*
  • Vero Cells / drug effects
  • Vero Cells / virology


  • Plant Extracts