Objective: To compare the efficacy of IUI husband in natural versus FSH stimulated cycles.
Design: Prospective, controlled study.
Materials and methods: IUI were performed in 57 infertile couples with natural cycles, and in 16 under FSH and GnRH stimulation (Short protocol). In stimulated patients also hCG and hydrogesteron were given. Indication in both groups was idiopathic infertility. Duration of infertility and the age were comparable. Semen preparation and ovarian monitoring were the same in 2 groups.
Results: Three pregnancies in 57 natural IUI cycles (5.3%) and 5 out of 16 cycles in stimulated women (31.2% per cycle-with one triple pregnancy).
Conclusion: In couples with idiopathic infertility FSH stimulation significantly increases rate of pregnancy and multiple gestation.