Tobacco use, particularly cigarette smoking, remains the leading cause of preventable illness and death in the United States. Studies have shown that increases in the price of cigarettes will decrease the prevalence of smoking and the number of cigarettes smoked both by youth and adults. However, the potential impact of price increases on minority and lower-income populations is an important consideration. This report summarizes the analysis of data for 14 years from the National Health Interview Survey (NHIS), which indicates that lower-income, minority, and younger populations would be more likely to reduce or quit smoking in response to a price increase in cigarettes.