Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 66 (4), 639-44

The Effects of 0.1 and 1.0 Per Cent Erythrocytes and Hemolysis on Serum Chemistry Values

The Effects of 0.1 and 1.0 Per Cent Erythrocytes and Hemolysis on Serum Chemistry Values

R H Laessig et al. Am J Clin Pathol.

Abstract

Changes in serum chemistry values as a result of incomplete removal of erythrocytes and in vitro hemolysis during the preparative process have been studied. Two levels of contamination, corresponding to removal of 99% and 99.9% of the erythrocytes, were used to examine the effects of both hemolyzed and intact cells. Forty chemical procedures and methods were considered. Serum LDH values were most strongly affected by hemolyzed erythrocytes. Potassium, creatine phosphokinase, aspartate aminotransferase, alanine aminotransferase, and iron showed smaller but significant effects due to the presence of 1% hemolyzed cells, with lesser effects observed at the 0.1% level. The presence of non-hemolyzed cells at either level did not significantly alter chemistry results.

Similar articles

See all similar articles

Cited by 1 article

Feedback