Screening for gestational diabetes mellitus. A perspective in 1998

Diabetes Care. 1998 Aug;21 Suppl 2:B14-8.


Gestational diabetes mellitus (GDM) was originally defined using statistics. It is appropriate to examine the current state of screening for gestational diabetes using a similar approach. This article reviews data supporting current recommendations for universal screening of pregnant women for GDM at 24-28 weeks using the 50-g 1-h oral glucose challenge. The advantages and disadvantages of several thresholds for abnormality are discussed, as are possible alternatives to the 50-g 1-h oral glucose challenge. Finally, recent improvements in the precision of portable blood glucose meters are reviewed, and recommendations for their use are advanced.

MeSH terms

  • Blood Glucose / analysis
  • Diabetes, Gestational / diagnosis*
  • Diabetes, Gestational / prevention & control
  • Fasting
  • Female
  • Glucose Tolerance Test*
  • Glycated Hemoglobin A / analysis
  • Humans
  • Mass Screening / methods*
  • Pregnancy
  • Pregnancy Trimester, Second
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Serum Albumin / analysis


  • Blood Glucose
  • Glycated Hemoglobin A
  • Serum Albumin
  • glycosylated serum albumin