Methotrexate for resistant chronic uveitis in children with juvenile rheumatoid arthritis

J Pediatr. 1998 Aug;133(2):266-8. doi: 10.1016/s0022-3476(98)70232-x.


We used low-dose methotrexate to treat seven children with juvenile rheumatoid arthritis-associated uveitis complicated by cataract and glaucoma or resistant to topical corticosteroid. The use of methotrexate decreased the severity of uveitis in six of seven patients and allowed for the discontinuation or reduction of corticosteroid drops.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Juvenile / complications*
  • Arthritis, Juvenile / drug therapy
  • Child
  • Child, Preschool
  • Chronic Disease
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Methotrexate / therapeutic use*
  • Treatment Outcome
  • Uveitis / complications
  • Uveitis / drug therapy*


  • Antirheumatic Agents
  • Immunosuppressive Agents
  • Methotrexate