Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis

Trends Microbiol. 1998 Jul;6(7):276-82. doi: 10.1016/s0966-842x(98)01306-7.


Murine gammaherpesvirus 68 (MHV-68) is a naturally occurring herpesvirus of wild rodents and is genetically related to human herpesvirus 8 and Epstein-Barr virus. The ability of MHV-68 to establish acute and persistent infection within laboratory mice offers a unique opportunity to investigate immunological and virological aspects of gammaherpesvirus pathogenesis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Disease Models, Animal
  • Gammaherpesvirinae*
  • Herpesviridae Infections*
  • Mice