Creating a national service for the diagnosis of meningococcal disease by polymerase chain reaction

Commun Dis Public Health. 1998 Mar;1(1):54-6.


The widening gap observed between numbers of culture confirmed and notified cases of meningococcal infection has driven the development of non-culture based polymerase chain reactions (PCRs) to enhance the detection of meningococcal disease. The development of a national PCR-based service increased the number of laboratory confirmed cases of meningococcal disease by 35% in the first year. Advancing technology in the laboratory is reducing in-lab processing time.

MeSH terms

  • England
  • Enzyme-Linked Immunosorbent Assay / methods*
  • Humans
  • Laboratories / organization & administration*
  • Meningococcal Infections / diagnosis*
  • Neisseria meningitidis / isolation & purification*
  • Reference Standards
  • Wales