The Bactrocera tryoni homologue of the Drosophila melanogaster sex-determination gene doublesex

Insect Mol Biol. 1998 Nov;7(4):355-66. doi: 10.1046/j.1365-2583.1998.740355.x.

Abstract

A homologue of the bifunctional sex-determining gene, doublesex (dsx), has been identified in the tephritid fruit fly, Bactrocera tryoni, and has been found to be expressed in a sex-specific manner in adult flies. The male- and female-specific cDNAs are identical at their 5' ends but differ at their 3' ends and appear to be the products of alternate splicing. The level of identity of the sex-specific DSX proteins of B. tryoni with the D. melanogaster DSX proteins, across the region corresponding to the DNA binding domain and the oligomerization domains, is greater than 85%. Four sequence motifs which are ten to thirteen bases identical to the TRA/TRA-2 binding sites (thirteen-nucleotide repeat sequences) are present in the female-specific exon of the B. tryoni dsx gene.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Binding Sites
  • Blotting, Northern
  • DNA, Complementary
  • DNA-Binding Proteins / genetics*
  • Diptera / genetics*
  • Drosophila Proteins*
  • Drosophila melanogaster / genetics
  • Exons
  • Female
  • Insect Proteins / genetics*
  • Male
  • Molecular Sequence Data
  • Ribonucleoproteins
  • Sequence Homology, Amino Acid
  • Sex Determination Processes

Substances

  • DNA, Complementary
  • DNA-Binding Proteins
  • DSX protein, Drosophila
  • Drosophila Proteins
  • Insect Proteins
  • Ribonucleoproteins
  • tra2 protein, Drosophila

Associated data

  • GENBANK/AF029675
  • GENBANK/AF029676
  • GENBANK/AF040077