Early growth response factor 1: a pleiotropic mediator of inducible gene expression

J Mol Med (Berl). 1998 Aug;76(9):613-6. doi: 10.1007/s001090050258.


The zinc-finger transcription factor, early growth response factor-1 (Egr-1) is an immediate-early gene product inducibly expressed in response to diverse stimuli. This review examines the emerging role of Egr-1 in vascular pathobiology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • DNA-Binding Proteins / physiology*
  • Early Growth Response Protein 1
  • Gene Expression Regulation*
  • Humans
  • Immediate-Early Proteins*
  • Retroviridae Proteins, Oncogenic / physiology*
  • Transcription Factors*


  • DNA-Binding Proteins
  • EGR1 protein, human
  • Early Growth Response Protein 1
  • Immediate-Early Proteins
  • Retroviridae Proteins, Oncogenic
  • Transcription Factors