Molecular and cell biological aspects of neuroendocrine tumors of the gastroenteropancreatic system

J Mol Med (Berl). 1998 Aug;76(9):637-47. doi: 10.1007/s001090050261.


Neurons and neuroendocrine cells share a variety of common characteristics. Cell and molecular biological studies in recent years have improved our understanding of physiological and pathophysiological processes such as cellular growth, adhesion, and secretion of neuroendocrine cells. Here we review current findings from the area of basic research and from current clinical research relevant to improving the diagnosis and therapy of neuroendocrine tumors of the gastroenteropancreatic system.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cell Division
  • Forecasting
  • Humans
  • Intestinal Neoplasms* / diagnosis
  • Intestinal Neoplasms* / genetics
  • Intestinal Neoplasms* / therapy
  • Neoplasm Metastasis
  • Neuroendocrine Tumors* / diagnosis
  • Neuroendocrine Tumors* / genetics
  • Neuroendocrine Tumors* / therapy
  • Neurosecretory Systems
  • Pancreatic Neoplasms* / diagnosis
  • Pancreatic Neoplasms* / genetics
  • Pancreatic Neoplasms* / therapy
  • Receptors, Cell Surface / metabolism
  • Signal Transduction
  • Stomach Neoplasms* / diagnosis
  • Stomach Neoplasms* / genetics
  • Stomach Neoplasms* / therapy


  • Receptors, Cell Surface