Contact pemphigus induced by dihydrodiphenyltrichlorethane

Eur J Dermatol. 1998 Sep;8(6):442-3.

Abstract

We describe a case of contact pemphigus, a new subgroup of induced pemphigus. The disease is provoked by a chlorinated hydrocarbon pesticide: dihydrodiphenyltrichlorethane. We suspect that systemic absorption after the topical contact is responsible for the alteration of skin structure and activation of immunological mechanisms leading to blister formation and acantholysis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Agricultural Workers' Diseases / chemically induced*
  • DDT / adverse effects*
  • Dermatitis, Allergic Contact / diagnosis
  • Dermatitis, Allergic Contact / etiology*
  • Female
  • Follow-Up Studies
  • Humans
  • Insecticides / adverse effects*
  • Methylprednisolone / administration & dosage
  • Middle Aged
  • Patch Tests
  • Pemphigus / chemically induced*
  • Pemphigus / diagnosis

Substances

  • Insecticides
  • DDT
  • Methylprednisolone