Hox Proteins Meet More Partners

Curr Opin Genet Dev. 1998 Aug;8(4):423-9. doi: 10.1016/s0959-437x(98)80113-5.

Abstract

The Hox genes are clustered sets of homeobox-containing genes that play a central role in animal development. Recent genetic and molecular data suggest that Hox proteins interact with pre-existing homeodomain protein complexes. These complexes may help to regulate Hox activity and Hox specificity, and help cells to interpret signaling cascades during development.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • DNA / metabolism
  • Homeodomain Proteins / metabolism
  • Homeodomain Proteins / physiology*
  • Signal Transduction*

Substances

  • Homeodomain Proteins
  • DNA