Abstract
We report the identification of a mouse cDNA Tpd52l1 (tumor protein D52-like 1), which represents the first demonstrated orthologue of the human TPD52L1 (alias D53) gene, a member of the breast carcinoma-associated TPD52 (alias D52) gene family. In situ hybridization mapping located the Tpd52l1 gene to chromosome 10A4-10B2. Since the TPD52L1 gene is found at human chromosome 6q22-->q23, the mouse and human TPD52L1 loci are syntenically conserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Breast Neoplasms / genetics
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Chromosome Mapping*
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Female
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Gene Library
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Humans
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Male
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Mice / genetics*
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Molecular Sequence Data
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Multigene Family
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Neoplasm Proteins / chemistry
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Neoplasm Proteins / genetics*
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Sequence Alignment
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Sequence Homology, Amino Acid
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Stem Cells
Substances
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Neoplasm Proteins
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TPD52 protein, human
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TPD52L1 protein, human
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Tpd52 protein, mouse