Identification and in situ hybridization mapping of a mouse Tpd52l1 (D53) orthologue to chromosome 10A4-B2

Cytogenet Cell Genet. 1998;81(3-4):199-201. doi: 10.1159/000015029.

Abstract

We report the identification of a mouse cDNA Tpd52l1 (tumor protein D52-like 1), which represents the first demonstrated orthologue of the human TPD52L1 (alias D53) gene, a member of the breast carcinoma-associated TPD52 (alias D52) gene family. In situ hybridization mapping located the Tpd52l1 gene to chromosome 10A4-10B2. Since the TPD52L1 gene is found at human chromosome 6q22-->q23, the mouse and human TPD52L1 loci are syntenically conserved.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Breast Neoplasms / genetics
  • Chromosome Mapping*
  • Female
  • Gene Library
  • Humans
  • Male
  • Mice / genetics*
  • Molecular Sequence Data
  • Multigene Family
  • Neoplasm Proteins / chemistry
  • Neoplasm Proteins / genetics*
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Stem Cells

Substances

  • Neoplasm Proteins
  • TPD52 protein, human
  • TPD52L1 protein, human
  • Tpd52 protein, mouse

Associated data

  • GENBANK/AF004428