Abstract
This study examined the hemodynamic effects of arbutamine, a synthetic catecholamine, in 12 patients with and 7 patients without coronary artery disease. Arbutamine produced a balanced positive inotropic (increase in left ventricular dp/dt) and chronotropic effect (increase in heart rate).
MeSH terms
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Adult
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Angina Pectoris / diagnosis*
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Cardiac Catheterization
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Cardiotonic Agents* / administration & dosage
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Catecholamines* / administration & dosage
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Coronary Disease / diagnosis*
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Dose-Response Relationship, Drug
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Electrocardiography / drug effects
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Female
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Heart Rate / drug effects
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Hemodynamics / drug effects*
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Humans
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Infusion Pumps
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Male
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Middle Aged
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Myocardial Contraction / drug effects
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Sensitivity and Specificity
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Tomography, Emission-Computed, Single-Photon
Substances
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Cardiotonic Agents
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Catecholamines
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arbutamine