Rhinal cortex ablations fail to disrupt reinforcer devaluation effects in rhesus monkeys (Macaca mulatta)

Behav Neurosci. 1998 Aug;112(4):1020-5. doi: 10.1037//0735-7044.112.4.1020.

Abstract

Studies have shown that excitotoxic lesions of the amygdala attenuate reinforcer devaluation effects in monkeys and rats. Because the rhinal (i.e., entorhinal and perirhinal) cortex has prominent reciprocal connections with the amygdala and has been suggested to store knowledge about objects, it is possible that it too composes part of the critical circuitry subserving learning about objects and their associated reinforcement value. To test this possibility, rhesus monkeys with rhinal cortex removals as well as unoperated controls were tested using a reinforcer devaluation procedure. Monkeys with rhinal cortex removals and controls, unlike those with amygdala lesions, tended to avoid displacing objects overlying a devalued food. These results indicate that the rhinal cortex is not a critical part of the neural circuitry mediating the effects of reinforcer devaluation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Analysis of Variance
  • Animals
  • Appetitive Behavior / physiology
  • Association Learning / physiology*
  • Cerebral Cortex / physiology*
  • Discrimination Learning / physiology
  • Entorhinal Cortex / physiology
  • Food
  • Limbic System / physiology*
  • Macaca mulatta
  • Neural Pathways / physiology
  • Reinforcement, Psychology*
  • Satiation / physiology