Primary structure and characterization of a bullfrog visual pigment contained in small single cones

Comp Biochem Physiol B Biochem Mol Biol. 1998 Mar;119(3):585-91. doi: 10.1016/s0305-0491(98)00032-7.


A cDNA fragment encoding a putative visual pigment (FCV pigment) was isolated from the bullfrog, Rana catesbeiana. Its deduced amino acid sequence shows high similarities to those of short wavelength-sensitive pigments such as human blue-, chicken violet- and goldfish ultraviolet-sensitive pigments. An antiserum against its C-terminal amino acid sequence recognized the outer segments of small cone photoreceptor cells without oil droplets. It is suggested that the FCV pigment is a short wavelength-sensitive pigment contained in small single cones which have not been characterized previously.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Chickens
  • DNA, Complementary
  • Evolution, Molecular
  • Goldfish
  • Humans
  • Molecular Sequence Data
  • Phylogeny
  • Rana catesbeiana
  • Recombinant Proteins / biosynthesis
  • Recombinant Proteins / chemistry
  • Retinal Cone Photoreceptor Cells / chemistry
  • Retinal Cone Photoreceptor Cells / metabolism*
  • Retinal Pigments / biosynthesis
  • Retinal Pigments / chemistry*
  • Retinal Pigments / genetics*
  • Sequence Alignment
  • Sequence Homology, Amino Acid


  • DNA, Complementary
  • Recombinant Proteins
  • Retinal Pigments