Management of pancreatic endocrine tumors in patients with multiple endocrine neoplasia type 1

Surg Oncol Clin N Am. 1998 Oct;7(4):881-91.

Abstract

The rationale for a multifaceted operative procedure in all MEN 1 patients with pancreaticoduodenal neuroendocrine disease who present without liver metastases is presented. The results in 36 patients with MEN 1 ZES are encouraging in that more than two-thirds are eugastrinemic and none have liver metastases after follow-up as long as 20 years.

Publication types

  • Review

MeSH terms

  • Adult
  • Duodenal Neoplasms / diagnostic imaging
  • Duodenal Neoplasms / surgery*
  • Female
  • Follow-Up Studies
  • Gastrins / antagonists & inhibitors
  • Hormones
  • Humans
  • Liver Neoplasms / secondary
  • Male
  • Mass Screening
  • Multiple Endocrine Neoplasia Type 1 / surgery*
  • Neuroendocrine Tumors / diagnostic imaging
  • Neuroendocrine Tumors / secondary
  • Neuroendocrine Tumors / surgery*
  • Octreotide
  • Pancreatectomy
  • Pancreatic Neoplasms / diagnostic imaging
  • Pancreatic Neoplasms / surgery*
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Zollinger-Ellison Syndrome / surgery

Substances

  • Gastrins
  • Hormones
  • Radiopharmaceuticals
  • Octreotide