Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: comparison with [(15)O]H2O positron emission tomography in humans

J Cereb Blood Flow Metab. 1998 Sep;18(9):935-40. doi: 10.1097/00004647-199809000-00002.


In six young, healthy volunteers, a novel method to determine cerebral blood flow (CBF) using magnetic resonance (MR) bolus tracking was compared with [(15)O]H2O positron emission tomography (PET). The method yielded parametric CBF images with tissue contrast in good agreement with parametric PET CBF images. Introducing a common conversion factor, MR CBF values could be converted into absolute flow rates, allowing comparison of CBF values among normal subjects.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cerebrovascular Circulation / physiology*
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Oxygen Radioisotopes
  • Reference Values
  • Tomography, Emission-Computed / methods*
  • Water / metabolism


  • Oxygen Radioisotopes
  • Water