Sequence variation: looking for effects of genetic linkage

Curr Biol. 1998 Sep 10;8(18):R658-61. doi: 10.1016/s0960-9822(07)00416-2.


Selection at linked loci probably reduces the variability of genes in regions of infrequent recombination. Detailed sequence information is needed to test possible causes of this effect; such information is now becoming available, but its interpretation can be difficult.

Publication types

  • Review

MeSH terms

  • Animals
  • Base Sequence
  • Crosses, Genetic
  • Genetic Linkage*
  • Genetic Variation*
  • Models, Genetic*
  • Plants / genetics
  • Selection, Genetic