Alveolar soft part sarcoma of the head and neck region

Ann Otol Rhinol Laryngol. 1998 Sep;107(9 Pt 1):810-4. doi: 10.1177/000348949810700914.


Alveolar soft part sarcoma is a soft tissue malignancy most often found in the extremities of young adults; when these tumors arise in the head and neck area, they usually appear in the orbit or the tongue. Their initial behavior is relatively indolent, but over time a sizable number of these tumors recur locally and metastasize; as such, they are best regarded as fully malignant neoplasms. The derivation of these tumors remains uncertain: while some have suggested that these are tumors of muscle origin and others have postulated a neuroendocrine origin, the evidence accumulated to date is conflicting, and so these neoplasms continue to be regarded as tumors of uncertain origin. Surgical excision is the mainstay of therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Humans
  • Sarcoma, Alveolar Soft Part / pathology*
  • Sarcoma, Alveolar Soft Part / surgery
  • Tongue / pathology
  • Tongue / surgery
  • Tongue Neoplasms / pathology*
  • Tongue Neoplasms / surgery