Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

Pharmacol Rev. 1998 Sep;50(3):387-412.

Authors

K Ito¹, T Iwatsubo, S Kanamitsu, K Ueda, H Suzuki, Y Sugiyama

Affiliation

¹ Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

PMID: 9755288

No abstract available

Publication types

Review

MeSH terms

Animals
Area Under Curve
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System / metabolism*
Drug Administration Routes
Drug Interactions*
Humans
Liver / metabolism*
Models, Biological
Pharmacokinetics*

Substances

Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System