Lung transplantation for cystic fibrosis

Clin Chest Med. 1998 Sep;19(3):535-54, vii. doi: 10.1016/s0272-5231(05)70099-x.


Lung transplantation currently stands as the only therapeutic option that carries the potential to restore patients with advanced cystic fibrosis to a more normal state of health. Nonetheless, the procedure carries significant risk and median survival following transplantation is only 5 years. This article discusses the currently achievable outcomes and the common short-comings of transplantation. Strategies to optimize outcomes through appropriate patient selection, use of living donors, and novel research initiatives are discussed.

Publication types

  • Review

MeSH terms

  • Cystic Fibrosis / complications
  • Cystic Fibrosis / microbiology
  • Cystic Fibrosis / physiopathology
  • Cystic Fibrosis / surgery*
  • Diabetes Complications
  • Exercise Tolerance
  • Graft Rejection
  • Humans
  • Liver Cirrhosis / complications
  • Living Donors
  • Lung Transplantation* / statistics & numerical data
  • Nutritional Physiological Phenomena
  • Osteoporosis / complications
  • Patient Selection
  • Quality of Life
  • Respiration, Artificial
  • Treatment Outcome