Acceptance Program Guidelines. Chemotherapeutic agents to slow or arrest periodontitis. Council on Scientific Affairs. American Dental Association

J Periodontol. 1998 Sep;69(9):1076-80. doi: 10.1902/jop.1998.69.9.1076.


These Guidelines apply to products used to slow or arrest periodontitis. The periodontal diseases represent a wide array of infections characterized by variable microbial clusters and host susceptibility factors that may require different therapeutic approaches. There are two basic ways to control periodontitis: 1) target the putative microbial components with anti-infective strategies; or 2) strengthen or suppress the host response with host modulation agents. Products that are designed for the prevention and/or control of gingivitis are addressed elsewhere and are not considered in these guidelines.

MeSH terms

  • Adjuvants, Immunologic / therapeutic use
  • Anti-Bacterial Agents / therapeutic use*
  • Bacteria / drug effects
  • Chemoprevention
  • Clinical Trials as Topic / methods*
  • Humans
  • Periodontitis / microbiology
  • Periodontitis / prevention & control*
  • Research Design*


  • Adjuvants, Immunologic
  • Anti-Bacterial Agents