Lymphocytic interstitial pneumonitis preceding polyarticular juvenile rheumatoid arthritis

Clin Exp Rheumatol. 1998 Sep-Oct;16(5):617-9.

Abstract

We describe the case of a 12-year-old girl who developed lymphocytic interstitial pneumonitis at 2 years of age which preceded polyarticular rheumatoid factor (RF) positive juvenile arthritis. Her disease had a chronic active course, but showed a good response to combination therapy. The pathogenesis of these two immune processes and of the lung involvement in juvenile arthritis is discussed.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Juvenile / diagnosis
  • Arthritis, Juvenile / drug therapy
  • Arthritis, Juvenile / etiology*
  • Biopsy
  • Child
  • Drug Therapy, Combination
  • Female
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Lung / diagnostic imaging
  • Lung / pathology
  • Lung Diseases, Interstitial / complications*
  • Lung Diseases, Interstitial / diagnosis
  • Lung Diseases, Interstitial / drug therapy
  • Lymphocytosis / complications*
  • Lymphocytosis / diagnosis
  • Lymphocytosis / drug therapy
  • Methotrexate / therapeutic use
  • Prednisone / therapeutic use
  • Tomography, X-Ray Computed

Substances

  • Anti-Inflammatory Agents
  • Antirheumatic Agents
  • Hydroxychloroquine
  • Prednisone
  • Methotrexate