Lepromatous uveitis diagnosed by iris biopsy

Graefes Arch Clin Exp Ophthalmol. 1998 Sep;236(9):717-9. doi: 10.1007/s004170050147.

Abstract

Ocular leprosy is rarely seen in developed countries. We report the long-term follow-up of a patient with bilateral uveitis, glaucoma, and keratitis. Skin, iris and aqueous humor biopsies disclosed abundant Wade-Fite-positive organisms consistent with Mycobacterium leprae. Leprosy must be considered in the differential diagnosis of keratitis and uveitis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Aqueous Humor / microbiology
  • Biopsy
  • DNA, Bacterial / analysis
  • Drug Therapy, Combination
  • Eye Infections, Bacterial / diagnosis*
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / microbiology
  • Glaucoma / diagnosis
  • Glaucoma / microbiology
  • Humans
  • Iris / microbiology
  • Iris / pathology*
  • Keratitis / diagnosis
  • Keratitis / microbiology
  • Leprostatic Agents / therapeutic use
  • Leprosy, Lepromatous / diagnosis*
  • Leprosy, Lepromatous / drug therapy
  • Leprosy, Lepromatous / microbiology
  • Male
  • Mycobacterium leprae / genetics
  • Mycobacterium leprae / isolation & purification*
  • Polymerase Chain Reaction
  • Skin / microbiology
  • Uveitis, Anterior / diagnosis*
  • Uveitis, Anterior / drug therapy
  • Uveitis, Anterior / microbiology

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • Leprostatic Agents