Development of advanced pulmonary vascular disease in D-transposition of the great arteries after the neonatal arterial switch operation

Tex Heart Inst J. 1998;25(3):201-5.


We report the case of a neonate with D-transposition of the great arteries who, after undergoing an uneventful arterial switch operation at the age of 4 days, was found at the age of 42 months to have developed advanced pulmonary vascular disease. Because the arterial switch operation was performed when our patient was only 4 days old, this case challenges the hypothesis that postnatal hemodynamics alone dictate the development of advanced pulmonary vascular disease in infants and children with transposition of the great arteries.

Publication types

  • Case Reports

MeSH terms

  • Follow-Up Studies
  • Humans
  • Hypertension, Pulmonary / diagnosis
  • Hypertension, Pulmonary / etiology*
  • Hypertension, Pulmonary / physiopathology
  • Infant, Newborn
  • Postoperative Complications / diagnosis
  • Postoperative Complications / etiology*
  • Postoperative Complications / physiopathology
  • Pulmonary Circulation / physiology
  • Time Factors
  • Transposition of Great Vessels / surgery*