New goals for the U.S. Human Genome Project: 1998-2003

Science. 1998 Oct 23;282(5389):682-9. doi: 10.1126/science.282.5389.682.


The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-98. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, 2 years ahead of previous projections. In the course of completing the sequence, a "working draft" of the human sequence will be produced by the end of 2001. The plan also includes goals for sequencing technology development; for studying human genome sequence variation; for developing technology for functional genomics; for completing the sequence of Caenorhabditis elegans and Drosophila melanogaster and starting the mouse genome; for studying the ethical, legal, and social implications of genome research; for bioinformatics and computational studies; and for training of genome scientists.

MeSH terms

  • Animals
  • Bioethics
  • Computational Biology
  • Databases, Factual
  • Databases, Nucleic Acid
  • Federal Government
  • Genetic Research
  • Genetic Variation
  • Genome
  • Genome, Human
  • Human Genome Project* / economics
  • Human Genome Project* / organization & administration
  • Humans
  • Information Dissemination
  • International Cooperation
  • Internationality
  • Molecular Biology / education
  • Point Mutation
  • Polymorphism, Genetic
  • Sequence Analysis, DNA / economics
  • Sequence Analysis, DNA / methods
  • Sociology
  • Species Specificity
  • Time Factors
  • United States