[Why is the DNA-strand-breaker, PCNDAC, effective to solid tumors?]

Tanpakushitsu Kakusan Koso. 1998 Oct;43(13):1981-9.
[Article in Japanese]
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Apoptosis
  • Cytarabine / analogs & derivatives*
  • Cytarabine / pharmacokinetics
  • Cytarabine / pharmacology
  • DNA Damage
  • DNA, Neoplasm / metabolism
  • Drug Design
  • Gene Deletion
  • Genes, p53 / genetics
  • Humans
  • Mice
  • Mice, Nude
  • Necrosis
  • Neoplasms / genetics
  • Neoplasms / pathology*
  • Point Mutation
  • Prodrugs*
  • RNA, Neoplasm / metabolism

Substances

  • DNA, Neoplasm
  • Prodrugs
  • RNA, Neoplasm
  • Cytarabine
  • 2'-cyano-2'-deoxyarabinofuranosylcytosine