Prospective study of antibiotic prescribing for children

Can Fam Physician. 1998 Sep;44:1850-6.


Objectives: To observe the frequency with which children in outpatient primary care settings are prescribed antibiotics and to investigate why these antibiotics are prescribed. To compare the prescribing behaviour of family doctors, primary care pediatricians, and urgent care physicians and to determine where refinements in management are most needed to reduce the number of antibiotic prescriptions appropriately.

Design: Prospective study using a data entry form with mostly closed-ended questions.

Setting: Ten primary care offices in urban south-central and eastern Ontario: five family practices, three pediatric practices, and two urgent care centres (UCC).

Participants: Every child younger than 16 years visiting these offices during a 3-week period in February and March 1997.

Main outcome measures: Frequency, clinical indications, and nature of the antibiotics prescribed.

Results: There were 4344 observed visits. Of 1706 antibiotic prescriptions, 1481 were for 10 days, and 1577 (92%) were for acute respiratory infections, 920 (53%) specifically for acute otitis media (AOM). Full courses of antibiotics were given immediately (i.e., without test results) to 321 (76%) of 425 children with pharyngitis. Antibiotics were prescribed for 145 (90%) of 163 children with bronchitis. Urgent care physicians were significantly more likely than pediatricians or family physicians to prescribe immediate antibiotics and to disregard guidelines when choosing antibiotics for uncomplicated AOM.

Conclusions: Three diagnoses accounted for 82% of antibiotic prescriptions: AOM, pharyngitis, and bronchitis. Physicians should be more selective when deciding whether, and for how long, to prescribe antibiotics for those three common conditions. Substantial reductions in antibiotic use will require changes in how physicians manage suspected AOM, the most common indication for antibiotics.

MeSH terms

  • Acute Disease
  • Adolescent
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Drug Prescriptions / statistics & numerical data*
  • Drug Utilization / statistics & numerical data*
  • Emergency Medicine / statistics & numerical data*
  • Family Practice / statistics & numerical data*
  • Guideline Adherence / statistics & numerical data
  • Health Services Research
  • Humans
  • Infant
  • Infant, Newborn
  • Ontario
  • Otitis Media / drug therapy
  • Pediatrics / statistics & numerical data*
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians' / statistics & numerical data
  • Prospective Studies
  • Respiratory Tract Infections / drug therapy
  • Surveys and Questionnaires


  • Anti-Bacterial Agents