Recommendations for prevention and control of hepatitis C virus (HCV) infection and HCV-related chronic disease. Centers for Disease Control and Prevention

MMWR Recomm Rep. 1998 Oct 16;47(RR-19):1-39.


These recommendations are an expansion of previous recommendations for the prevention of hepatitis C virus (HCV) infection that focused on screening and follow-up of blood, plasma, organ, tissue, and semen donors (CDC. Public Health Service inter-agency guidelines for screening donors of blood, plasma, organs, tissues, and semen for evidence of hepatitis B and hepatitis C. MMWR 1991;40[No. RR-41;1-17). The recommendations in this report provide broader guidelines for a) preventing transmission of HCV; b) identifying, counseling, and testing persons at risk for HCV infection; and c) providing appropriate medical evaluation and management of HCV-infected persons. Based on currently available knowledge, these recommendations were developed by CDC staff members after consultation with experts who met in Atlanta during July 15-17, 1998. This report is intended to serve as a resource for health-care professionals, public health officials, and organizations involved in the development, delivery, and evaluation of prevention and clinical services.

Publication types

  • Guideline
  • Practice Guideline

MeSH terms

  • Algorithms
  • DNA, Viral / analysis
  • Hepacivirus / isolation & purification
  • Hepatitis C, Chronic / blood
  • Hepatitis C, Chronic / epidemiology
  • Hepatitis C, Chronic / prevention & control*
  • Humans
  • Infectious Disease Transmission, Patient-to-Professional / prevention & control
  • Risk Factors
  • Serologic Tests
  • United States / epidemiology


  • DNA, Viral