Midfacial degloving is known to provide excellent exposure of the central compartment of the anterior and middle cranial fossae without facial incisions. In this study, an endoscope was adapted for midfacial degloving technique in the medial maxillectomy with ethmoidectomy in five patients with sinonasal malignancy. Meticulous and safe manipulation in the medial and inferior aspect of the orbit, sphenoid sinus and olfactory fossa can be obtained by endoscopic management without serious complications. This procedure, employing an endoscope, offers accurate and safe resection of selected cases with the sinonasal malignancy.