Experimental bifurcation aneurysm: a model for in vivo evaluation of endovascular techniques

Minim Invasive Neurosurg. 1998 Sep;41(3):129-32. doi: 10.1055/s-2008-1052027.


An experimental aneurysm model for in vivo testing of endovascular techniques is described. The aneurysm is produced surgically in the neck of the rabbit by partial anastomosis of the left to the right common carotid artery, thus creating an arterial bifurcation. Subsequently, a venous pouch is sutured into the artificial bifurcation. The size of the arteries, coagulation profile and hemodynamic features in this aneurysm model closely mimic human conditions. Surgical technique and our preliminary experience with this model are discussed.

MeSH terms

  • Animals
  • Carotid Artery Diseases / diagnostic imaging
  • Carotid Artery Diseases / therapy*
  • Carotid Artery, Common
  • Cerebral Angiography
  • Disease Models, Animal*
  • Embolization, Therapeutic / instrumentation*
  • Humans
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / therapy*
  • Rabbits