Xanthine urolithiasis in a dachshund

Vet Rec. 1998 Oct 10;143(15):420-3. doi: 10.1136/vr.143.15.420.

Abstract

Calculi were located in the kidneys, the ureters and the bladder of a two-year-old male dachshund. The yellow-greenish calculi developed as a result of impaired transformation of xanthine to uric acid resulting in an increased concentration of xanthine in the urine. The cause of the impaired catabolism of xanthine was probably a disorder of the xanthine oxidase enzyme, which catalyses the transformation of xanthine to uric acid.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Dog Diseases / enzymology*
  • Dog Diseases / pathology
  • Dogs
  • Male
  • Uric Acid
  • Urinary Calculi / enzymology
  • Urinary Calculi / pathology
  • Urinary Calculi / veterinary*
  • Xanthine / metabolism*
  • Xanthine Oxidase / metabolism

Substances

  • Xanthine
  • Uric Acid
  • Xanthine Oxidase