Hypoglycaemic activity of an HMG-containing flavonoid glucoside, chamaemeloside, from Chamaemelum nobile

Planta Med. 1998 Oct;64(7):612-4. doi: 10.1055/s-2006-957532.

Abstract

The 3-hydroxy-3-methylglutaric acid (HMG) containing flavonoid glucoside chamaemeloside, has been determined to have in vivo hypoglycaemic activity comparable to that of free HMG. An improved isolation scheme for obtaining chamaemeloside from Chamaemelum nobile is presented.

MeSH terms

  • Animals
  • Asteraceae / chemistry*
  • Blood Glucose / analysis
  • Cell Line
  • Glucose Tolerance Test
  • Glucosides / chemistry
  • Glucosides / isolation & purification
  • Glucosides / pharmacology*
  • Hypoglycemic Agents / chemistry
  • Hypoglycemic Agents / isolation & purification
  • Hypoglycemic Agents / pharmacology*
  • Male
  • Mice
  • Plants, Medicinal / chemistry*

Substances

  • Blood Glucose
  • Glucosides
  • Hypoglycemic Agents
  • chamaemeloside