Neural disease: Drosophila degenerates for a good cause

Curr Biol. 1998 Nov 5;8(22):R809-11. doi: 10.1016/s0960-9822(07)00506-4.

Abstract

Human neurodegenerative disorders are typified by late onset cell loss in specific brain regions and stereotypic neuroanatomical and behavioral aberrations. Recent studies suggest that molecular genetic approaches in Drosophila may shed important new light on conserved mechanisms underlying such disorders.

Publication types

  • Review

MeSH terms

  • Animals
  • Drosophila / genetics*
  • Genes, Insect*
  • Glutamic Acid
  • Humans
  • Microsatellite Repeats
  • Mutation
  • Nerve Degeneration / genetics*

Substances

  • Glutamic Acid