Dendritic localization of mRNAs

Curr Opin Neurobiol. 1998 Oct;8(5):600-6. doi: 10.1016/s0959-4388(98)80087-1.


The dendritic localization of mRNAs has been proposed to underlie the structural and functional polarity of neurons, as well as certain aspects of synaptic plasticity. Even though there is no conclusive evidence that such a localization is a physiological requirement, studies of mRNA localization in relation to function in other cell types and recent experiments on synaptic plasticity suggest that this proposal may be correct.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Polarity / physiology
  • Dendrites / chemistry*
  • Dendrites / physiology*
  • Nerve Tissue Proteins / genetics
  • Neuronal Plasticity / physiology
  • Neurons / chemistry
  • Neurons / cytology
  • Neurons / ultrastructure
  • RNA, Messenger / analysis*


  • Nerve Tissue Proteins
  • RNA, Messenger