Abnormal somatosensory homunculus in dystonia of the hand

Ann Neurol. 1998 Nov;44(5):828-31. doi: 10.1002/ana.410440520.


Abnormalities of the sensory system have been proposed as causative factors for dystonia By mapping the human cortical hand somatosensory area of 6 patients with focal dystonia of the hand, we found an abnormality of the normal homuncular organization of the finger representations in the primary somatosensory cortex (S1). Although a remote antecedent event or even a developmental anomaly cannot entirely be ruled out, our findings may support the concept that abnormal plasticity is involved in the development of dystonia.

MeSH terms

  • Brain / anatomy & histology
  • Brain / physiology
  • Brain / physiopathology*
  • Brain Mapping*
  • Dystonia / pathology
  • Dystonia / physiopathology*
  • Fingers
  • Functional Laterality
  • Hand
  • Humans
  • Middle Aged
  • Motor Activity
  • Reference Values
  • Somatosensory Cortex / physiology
  • Somatosensory Cortex / physiopathology*