Setback phenomenon in autism and long-term prognosis

Acta Psychiatr Scand. 1998 Oct;98(4):296-303. doi: 10.1111/j.1600-0447.1998.tb10087.x.


From among the subjects of a follow-up study on cases of autism conducted by the authors in 1990, 179 cases for which precise records were available on the infancy period were selected for evaluation of the relationship between the occurrence of setback phenomenon in infancy and long-term prognosis. The following results were obtained: (i) a significantly higher rate of epilepsy among the setback group compared to the non-setback group; and (ii) a significantly lower level of language development among the setback group upon entering elementary school compared to the non-setback group, although the difference between the present levels of adaptation of the two groups was not significant. Factors determining the long-term prognosis of the setback group are discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autistic Disorder / complications
  • Autistic Disorder / diagnosis*
  • Autistic Disorder / psychology*
  • Child
  • Cognition Disorders / diagnosis
  • Cognition Disorders / etiology
  • Disease Progression
  • Epilepsy / complications
  • Epilepsy / diagnosis
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Predictive Value of Tests
  • Prognosis
  • Time Factors