The effects of a physical training program on patients with osteoarthritis of the knees

Arch Phys Med Rehabil. 1998 Nov;79(11):1421-7. doi: 10.1016/s0003-9993(98)90238-6.


Objective: To investigate physical function in patients with severe osteoarthritis (OA) of the knees during and after a general physical training program.

Design: Randomized control trial, blinded observer, follow-up at 3 months and 1 year.

Setting: Outpatient clinic.

Patients: Consecutive sample of 25 patients (3 men, 22 women) with OA of the knees according to the criteria of the American College of Rheumatology (ACR). Two patients (8%) failed to complete the study. There were no withdrawals for adverse effects.

Intervention: Twelve patients received training in groups of 6, twice a week for 3 months. Training focused on general fitness, balance, coordination, stretching, and lower extremity muscle strength, and included a daily home exercise program.

Main outcome measures: Muscle strength across the knee (extension and flexion), Algofunctional Index (AFI), pain (0 to 10 point scale), walking speed, clinical findings.

Results: Patients participated in 96 of 96 assessments (100%) and in 218 of 280 training sessions (77.9%). From baseline to 3 months, isokinetic quadriceps strength (30 degrees/sec) improved 20% (confidence interval [CI] 2alpha = .05, 8% to 50%) in the least affected leg; isometric strength improved 21%. By 1 year, AFI had decreased 3.8 points (CI2alpha = .05, 1.0 to 7.0), pain had decreased 2.0 points (CI2alpha = 05, 0.0 to 4.0), and walking speed had increased 13% (CI2alpha = .05, 4% to 23%). There was an increase in the frequency of palpable joint effusions (p < .01) on the most affected side. Frequency of crepitus decreased on the least affected side (p < .01).

Conclusions: General physical training appears to be beneficial to patients with OA of the knee. As shown by the high compliance and low dropout frequency, such a program is feasible even in patients with severe OA of the knee.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Exercise Therapy*
  • Female
  • Humans
  • Knee Joint / physiopathology
  • Male
  • Middle Aged
  • Muscle, Skeletal / physiology
  • Osteoarthritis, Knee / physiopathology
  • Osteoarthritis, Knee / rehabilitation*
  • Postural Balance
  • Prospective Studies
  • Range of Motion, Articular
  • Single-Blind Method
  • Treatment Outcome