A clinical comparison of transscleral cyclophotocoagulation with neodymium: YAG and semiconductor diode lasers

Am J Ophthalmol. 1998 Nov;126(5):640-7. doi: 10.1016/s0002-9394(98)00228-1.


Purpose: To compare the efficacy of transscleral cyclophotocoagulation using a neodymium: YAG (Nd:YAG) or semiconductor diode laser in controlling intraocular pressure in patients with refractory glaucoma.

Methods: In a prospective study, 95 eyes of 91 patients with refractory glaucoma randomly received Nd:YAG or diode cyclophotocoagulation. Patients were followed for a mean of 10.4 months (10.42 +/- 3.16, mean +/- SD). We compared available data preoperatively and at 1 week, 1 month, 6 months, and 12 months postoperatively. Data analyzed were corrected visual acuity, intraocular pressure, and the type of glaucoma.

Results: There was a statistically significant decrease in intraocular pressure after both Nd:YAG and diode cyclophotocoagulation at each time period. However, there were no significant differences in postoperative intraocular pressure or visual acuity change between Nd:YAG and diode procedures.

Conclusions: Compared with the Nd:YAG laser for transscleral cyclophotocoagulation, the diode laser has technological advantages including portability, durability, and smaller size, while providing equivalent postoperative intraocular pressure and visual acuity change.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Ciliary Body / surgery*
  • Female
  • Follow-Up Studies
  • Glaucoma / surgery*
  • Humans
  • Intraocular Pressure*
  • Laser Coagulation / methods*
  • Male
  • Middle Aged
  • Postoperative Complications
  • Prospective Studies
  • Sclera
  • Treatment Outcome
  • Visual Acuity