Delayed delivery of multiple gestations: maternal and neonatal outcomes

Am J Obstet Gynecol. 1998 Nov;179(5):1145-9. doi: 10.1016/s0002-9378(98)70122-x.

Abstract

Objective: The study's aims were to compare neonatal outcomes and to describe maternal complications in patients who underwent delayed delivery of twins or triplets in a preterm gestation.

Study design: A retrospective review was performed on 5 sets of twins and 2 sets of triplets. Maternal morbidity was described. Neonatal outcomes were compared in the initial and subsequent delivery groups.

Results: The percentage of surviving firstborns was 57%, compared with 78% among latter-born infants. The average gestational age of the initial delivery group was 22.6 weeks (18.9-24.7 weeks); gestational age was 27.4 weeks (19.3-37.9 weeks) for the subsequent group (P <.05), a difference of 32.6 days. The average weight gain was 556.1 g. Serious neonatal complications were less frequent among the subsequently delivered siblings (P <.05), and the mean difference in neonatal hospital stay was 77.3 days, with a range of 62.5 to 139.8 (P <.5). Adverse maternal outcomes were represented by 3 patients with abruptio placentae and 3 patients with intra-amniotic infection, 2 of whom had positive blood culture results.

Conclusion: On the basis of our experience with 7 multifetal pregnancies, delayed delivery has been demonstrated to increase the likelihood of survival and decrease morbidity among the latter-born siblings. Despite the risk of complications, these data support therapeutic interventions aimed at delayed delivery of subsequent fetuses in cases with the potential for significant morbidity and mortality.

MeSH terms

  • Cohort Studies
  • Delivery, Obstetric*
  • Female
  • Health Care Costs
  • Humans
  • Incidence
  • Infant, Newborn
  • Infant, Newborn, Diseases / epidemiology
  • Length of Stay
  • Maternal Welfare
  • Obstetric Labor Complications / epidemiology
  • Pregnancy
  • Pregnancy Outcome
  • Pregnancy, Multiple*
  • Retrospective Studies
  • Time Factors
  • Triplets
  • Twins
  • Weight Gain / physiology