First report of association of chronic pancreatitis, primary biliary cirrhosis, and systemic sclerosis

Dig Dis Sci. 1998 Nov;43(11):2426-8. doi: 10.1023/a:1026673930030.


We report an original observation of chronic pancreatitis associated with primary biliary cirrhosis and systemic sclerosis. The diagnosis of each of these conditions was unequivocally confirmed. Pancreatic involvement in this case was asymptomatic. The association of chronic pancreatitis with primary biliary cirrhosis has been previously reported and pancreatitis has been associated with other autoimmune disorders. We hypothesize about the underlying pathogenic mechanisms of chronic pancreatitis in our case.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Chronic Disease
  • Fatal Outcome
  • Female
  • Humans
  • Liver Cirrhosis, Biliary / diagnosis*
  • Pancreatitis / diagnosis*
  • Scleroderma, Systemic / diagnosis*